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To establish biomarkers of human ageing, 26 groups in 14 European countries have joined forces in the "European Study to Establish Biomarkers of Human Ageing (MARK-AGE)".
The scientific background is as follows: The rate of aging in humans is not uniform, age-related changes in body function or composition that serve as a measure of "biological" age and could predict the onset of age-related diseases and/or remaining lifespan are referred to as "biomarkers of aging". As part of the MARK-AGE project, a population study (3,700 subjects) is being conducted to identify a range of biomarkers of ageing. The range of candidate biomarkers to be tested includes (a) "classical", for which data from several smaller studies have already been published; (b) "novel", which are based on current preliminary data, and (c) "novel", which are based on current research into mechanistic aspects of ageing.